Monomeric E6AP-E6-p53 ternary complex
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 8r1f
Q-score: 0.316
Sandate CR, Chakraborty D, Kater L, Kempf G, Thomae NH
To Be Published
- Ubiquitin-protein ligase e3a (103 kDa, Protein from Homo sapiens)
- Monomeric e6ap-e6-p53 ternary complex (176 kDa, Complex from Homo sapiens)
- Ubiquitin-like protein smt3,protein e6 (31 kDa, Protein from Human papillomavirus type 16)
- Cellular tumor antigen p53 (46 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
Dimeric ternary structure of E6AP-E6-p53
Resolution: 3.99 Å
EM Method: Single-particle
Fitted PDBs: 8r1g
Q-score: 0.175
Sandate CR, Chakraborty D, Kater L, Kempf G, Thomae NH
To Be Published
- Ubiquitin-protein ligase e3a (103 kDa, Protein from Homo sapiens)
- Ubiquitin-like protein smt3,protein e6 (31 kDa, Protein from Human papillomavirus type 16)
- Cellular tumor antigen p53 (46 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dimeric e6ap-e6-p53 ternary complex (352 kDa, Complex from Homo sapiens)
Cryo-EM structure of MLE in complex with UUC RNA and ADP
Resolution: 3.62 Å
EM Method: Single-particle
Fitted PDBs: 8pjb
Q-score: 0.415
To Be Published
- Rna (5'-r(p*cp*up*cp*up*up*up*cp*up*u)-3') (Complex from Drosophila melanogaster)
- Complex of mle, uuc and adp (134 kDa, Complex)
- Dosage compensation regulator (Complex from Drosophila melanogaster)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Magnesium ion (24 Da, Ligand)
- Rna (5'-r(p*cp*up*cp*up*up*up*cp*up*u)-3') (3 kDa, RNA from Drosophila melanogaster)
Cryo-EM structure of MLE in complex with ADP:AlF4 and U10 RNA
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8b9g
Q-score: 0.513
To Be Published
- Mle in complex with adp:alf4 and u10 rna (133 kDa, Complex from Drosophila melanogaster)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Water (18 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Rna (5'-r(p*up*up*up*up*up*up*up*up*up*up*u)-3') (3 kDa, RNA from Drosophila melanogaster)
Cryo-EM structure of MLE in complex with ADP:AlF4 and UUC RNA
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 8b9i
Q-score: 0.469
To Be Published
- Rna (5'-r(p*cp*cp*up*cp*up*up*up*cp*up*up*u)-3') (3 kDa, RNA from Drosophila melanogaster)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Water (18 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Mle in complex with adp:alf4 and uuc rna (133 kDa, Complex from Drosophila melanogaster)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of MLE in complex with ADP:AlF4
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8b9j
Q-score: 0.416
To Be Published
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Mle in complex with adp:alf4 (130 kDa, Cellular component from Drosophila melanogaster)
Cryo-EM structure of MLE in complex with ADP:AlF4 and SL7modUUC RNA
Resolution: 4.04 Å
EM Method: Single-particle
Fitted PDBs: 8b9k
Q-score: 0.239
To Be Published
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Sl7moduuc (19 kDa, RNA from Drosophila melanogaster)
- Mle in complex with adp:alf4 and sl7moduuc rna (149 kDa, Complex from Drosophila melanogaster)
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8b9l
Q-score: 0.345
To Be Published
- Mle (130 kDa, Cellular component from Drosophila melanogaster)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
BAP1/ASXL1 bound to the H2AK119Ub Nucleosome
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8svf
Q-score: 0.383
Thomas JF, Valencia-Sanchez MI, Tamburri S, Gloor SL, Rustichelli S, Godinez-Lopez V, De Ioannes P, Lee R, Abini-Agbomson S, Gretarsson K, Burg JM, Hickman AR, Sun L, Gopinath S, Taylor HF, Sun ZW, Ezell RJ, Vaidya A, Meiners MJ, Cheek MA, Rice WJ, Svetlov V, Nudler E, Lu C, Keogh MC, Pasini D, Armache KJ
Sci Adv (2023) 9 pp. eadg9832-eadg9832 [ Pubmed: 37556531 DOI: doi:10.1126/sciadv.adg9832 ]
- Dna/rna (187-mer) (58 kDa, Macromolecule from synthetic construct)
- Polycomb group protein asxl1 (165 kDa, Protein from Homo sapiens)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Histone h2a type 1 (14 kDa, Protein from Xenopus laevis)
- Ubiquitin carboxyl-terminal hydrolase bap1 (80 kDa, Protein from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Dna/rna (327-mer) (102 kDa, Macromolecule from synthetic construct)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
- Bap1/asxl1 bound to the h2ak119ub nucleosome (Complex from Homo sapiens)
human RNA polymerase III pre-initiation complex closed DNA 1
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8ity
Q-score: 0.291
Hou H, Jin Q, Ren Y, Chen Z, Wang Q, Xu Y
Cell Res (2023) 33 pp. 565-568 [ DOI: doi:10.1038/s41422-023-00819-x Pubmed: 37165065 ]
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Transcription factor iiib 50 kda subunit (46 kDa, Protein from Homo sapiens)
- Rna polymerase iii pre-initiation complex closed complex 1 (Complex)
- Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 3 (46 kDa, Protein from Homo sapiens)
- Dna (Complex)
- Iron/sulfur cluster (351 Da, Ligand)
- Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 1 (43 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Dna (82-mer) (143 kDa, DNA from Homo sapiens)
- Transcription factor tfiiib component b'' homolog (294 kDa, Protein from Homo sapiens)
- Rna polymerase iii pre-initiation complex closed complex 1 (1 MDa, Complex from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Dna (82-mer) (143 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc4 (35 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 4 (159 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)